TASK #PROJ_004MASTER DIFFICULTY
CRISPR-Cas9 Off-Target CFD Scoring & Gene Regulation RLHF Preference Ranking
Publisher: GeneNexus Genomics Lab • 100% Pre-funded Escrow
00:42:00
$40.60 Earned Session
Technical Scope & Verification Criteria
Evaluate model calculations for PAM-adjacent vs distal guide RNA base mismatch penalties. Verify transcript impact predictions across exons, introns, and promoter regions for human genome assembly GRCh38.
Required Deliverable Acceptance Criteria
- Verify calculated CFD scores match validated cutting frequency formulas within 1% error margin.
- Audit gene annotation accuracy against Ensembl canonical transcript models.
- Provide pairwise preference justifications for RLHF dataset curation.